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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MLXIPL
All Species:
25.76
Human Site:
T738
Identified Species:
43.59
UniProt:
Q9NP71
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NP71
NP_116569.1
852
93073
T738
C
Q
Q
Q
L
P
A
T
G
V
P
I
T
H
Q
Chimpanzee
Pan troglodytes
XP_509441
819
90122
T704
C
Q
Q
L
L
P
A
T
G
V
P
V
T
R
R
Rhesus Macaque
Macaca mulatta
XP_001115131
390
43669
G277
P
P
E
D
A
Y
V
G
N
A
D
M
I
Q
P
Dog
Lupus familis
XP_546925
857
93734
T743
C
Q
Q
Q
L
P
A
T
G
V
P
I
T
H
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q99MZ3
864
94857
T750
C
Q
Q
Q
L
P
A
T
G
V
P
I
T
H
Q
Rat
Rattus norvegicus
Q6AXT8
471
49872
H330
H
P
P
A
P
G
V
H
P
P
A
P
G
V
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001104311
895
97370
T782
C
Q
E
Q
L
P
A
T
G
V
P
I
T
R
Q
Frog
Xenopus laevis
NP_001084764
548
60887
F435
I
T
K
D
G
N
K
F
P
L
C
N
T
S
V
Zebra Danio
Brachydanio rerio
XP_001338503
817
90800
T702
C
Q
E
Q
L
P
E
T
G
V
P
I
T
R
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_724328
836
92381
N717
L
H
S
I
L
P
A
N
G
A
P
V
T
R
Q
Honey Bee
Apis mellifera
XP_394429
1014
115124
T899
C
Q
S
M
L
P
A
T
G
A
P
I
S
R
H
Nematode Worm
Caenorhab. elegans
P41846
1009
112841
S891
L
Q
S
N
L
P
Q
S
S
A
P
S
S
S
S
Sea Urchin
Strong. purpuratus
XP_788672
1338
148936
R1225
V
K
G
V
E
Y
T
R
K
L
Q
S
D
R
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LVN1
1266
139556
L1012
I
S
E
L
R
N
S
L
G
V
V
N
S
A
A
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
41.6
42.9
87.7
N.A.
81.4
20.8
N.A.
N.A.
51.4
30.9
39.4
N.A.
20
29.5
25.5
21.1
Protein Similarity:
100
55.4
43.9
91.4
N.A.
85.7
29.3
N.A.
N.A.
60.7
41.6
53.5
N.A.
36.5
44.9
41.3
33.5
P-Site Identity:
100
73.3
0
100
N.A.
100
0
N.A.
N.A.
86.6
6.6
73.3
N.A.
46.6
60
26.6
0
P-Site Similarity:
100
86.6
13.3
100
N.A.
100
0
N.A.
N.A.
93.3
20
80
N.A.
53.3
66.6
40
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.5
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
34
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
8
0
50
0
0
29
8
0
0
8
8
% A
% Cys:
50
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% C
% Asp:
0
0
0
15
0
0
0
0
0
0
8
0
8
0
0
% D
% Glu:
0
0
29
0
8
0
8
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% F
% Gly:
0
0
8
0
8
8
0
8
65
0
0
0
8
0
0
% G
% His:
8
8
0
0
0
0
0
8
0
0
0
0
0
22
22
% H
% Ile:
15
0
0
8
0
0
0
0
0
0
0
43
8
0
0
% I
% Lys:
0
8
8
0
0
0
8
0
8
0
0
0
0
0
0
% K
% Leu:
15
0
0
15
65
0
0
8
0
15
0
0
0
0
0
% L
% Met:
0
0
0
8
0
0
0
0
0
0
0
8
0
0
0
% M
% Asn:
0
0
0
8
0
15
0
8
8
0
0
15
0
0
0
% N
% Pro:
8
15
8
0
8
65
0
0
15
8
65
8
0
0
8
% P
% Gln:
0
58
29
36
0
0
8
0
0
0
8
0
0
8
36
% Q
% Arg:
0
0
0
0
8
0
0
8
0
0
0
0
0
43
15
% R
% Ser:
0
8
22
0
0
0
8
8
8
0
0
15
22
15
8
% S
% Thr:
0
8
0
0
0
0
8
50
0
0
0
0
58
0
0
% T
% Val:
8
0
0
8
0
0
15
0
0
50
8
15
0
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
15
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _